입학안내

취업 · 산학협동

교수소개

  • HOME
  • 학과안내
  • 교수소개

탄탄한 실력과 전문성을 갖춘 열정적인 교수진

곽민규 교수

곽민규 교수

전공 :
생물물리학,미생물학,대사생화학 
전화 :
031-740-7418 
연구실 :
박애관 217호 
E-mail :
genie6@eulji.ac.kr

학력

  • 연세대학교 생활과학대학 식품영양학과 (식품영양학 전공) 이학사
  • 연세대학교 생활과학대학 식품영양학과 (임상영양학 전공) 이학석사
  • 서울대학교 자연과학대학 생명과학부 (미생물학/생물물리학 전공) 이학박사

연구 및 교육

  • 現 을지대학교 바이오융합대학 식품영양학과 조교수
  • 現 UN Habitat Specialized/Expert Committeeman for Korean National Committee (유엔 해비타트 한국위원회 전문위원)
  • 前 Universiti Malaysia Sabah (UMS, 말레이시아), Biotechnology Programme, Faculty of Science and Natural Resources, Visiting Professor
  • 前 성결대학교 파이데이아학부 특임교수/융합학부 바이오헬스케어시스템 융합전공 교수
  • 前 서울대학교 BK21플러스 생명과학고급인력양성사업단 선임연구원
  • 前 서울대학교 자연과학대학 미생물연구소 선임연구원
  • 前 서울대학교 BK21 생명과학고급인력양성사업단 박사후연수연구원
  • 前 서울대학교 자연과학대학 미생물연구소 박사후연수연구원
  • 前 서울대학교 자연과학대학 미생물연구소 연구원
  • 前 서울대학교 자연과학대학 생명과학부 대표조교 (교육공무원)
  • 前 연세대학교 생활과학대학 식품영양학과 조교

산학 경력 및 기타

  • 現/前 ㈜오카랩 (Orca Lab Co., Ltd.) 사외이사/㈜오카랩 (Orca Lab Co., Ltd.) 대표이사
  • 現/前 ㈜일위 (IRWEE Co., Ltd.) 現 사외이사/前 사내이사
  • 現 뉴스톱 (팩트체크 미디어 뉴스톱, NewsTof, Inc.) 전문 팩트체커
  • 現 ㈜토니모리 (TONYMOLY Co., Ltd.) 자문교수/기술고문
  • 現 ㈜에이투젠 (ATOGEN Co., Ltd.) 자문교수/기술고문
  • 現 코디팜영농법인㈜ (Cordyfarm Co., Ltd.) 자문교수/기술고문

학술활동 (※ 국제학회 운영 및 국제학술지 편집장)

  • 現 한국미생물학회 (The Microbiological Society of Korea) 정회원
  • 現 한국미생물·생명공학회 (The Korean Society for Microbiology and Biotechnology) 정회원
  • 現 한국분자·세포생물학회 정회원 (Korean Society for Molecular and Cellular Biology)
  • 現 한국식생활문화학회 (Korean Society of Food Culture) 평이사
  • 現 한국영양학회 (The Korean Nutrition Society) 정회원
  • 現 네이버 미생물학백과 (Naver Micropedia) 출판위원회 집필진
  • 現/前 Organizer, International Conference on Science
  • 現/前 General Co-Chair, International Congress on Science and Technology (ICST), Malaysia
  • 現 Review Editor, Frontiers in Microbiology, USA
  • 現 Editor, Journal of Anatomy Forecast, USA
  • 現 Biochemistry Advisory Board Editor, Cambridge Scholars Publishing (Registration Number: 04333775), United Kingdom

학술발표 (Symposium/Conference Presentation)

  • General Co-Chair, International Congress on Science and Technology 2019, December 5-7, 2019, Manila, Philippines (Scheduled)
  • Keynote Speaker, International Conference on Science and Natural Resources ICSNR2017, Apr 6, 2017, Kota Kinabalu, Malaysia, pp4: Benefits of cultural exposure and development of Korean perspective-kimchi and fermentation products
  • Biophysics Session Chairperson, International Congress on Science and Technology 2017, December 8-11, 2017 Bali, Indonesia: Structured Session 10 Frontiers in Biophysics
  • General Co-Chair/Organizer/Session Chair, International Congress on Science and Biotechnology 2018, December 6-8, 2018 Phuket, Thailand
  • Interaction between Fructose-1,6-Bisphosphate Aldolase and Glyceraldehyde-3-Phosphate Dehydrogenase Decreases Methylglyoxal Production, Eulji University, Republic of Korea, 46th Annual Meeting
  • Glutathione reductase is essential for growth and its overexpression leads to defective hyphal growth and attenuated virulence of Candida albicans, Seoul National University, Republic of Korea, The FEBS JOURNAL 282 (Suppl. 1), pp128 (P10-067), The 40th Congress of the Federation of European Biochemical Societies (FEBS Congress), The Biochemical Basis of Life, Berlin, Germany, July 4-9, 2015
  • Novel NAD (H)-linked methylglyoxal dehydrogenase is induced in glutathione-depleted Candida albicans, Seoul National University, Republic of Korea, The FEBS JOURNAL 282 (Suppl. 1), pp129 (P10-069), The 40th Congress of the Federation of European Biochemical Societies (FEBS Congress), The Biochemical Basis of Life, Berlin, Germany, July 4-9, 2015
  • Putrescine defect leads to G1-phase cell cycle arrest by methylglyoxal accumulation, Seoul National University, Republic of Korea, The FEBS JOURNAL 282 (Suppl. 1), pp227 (P11-027), The 40th Congress of the Federation of European Biochemical Societies (FEBS Congress), The Biochemical Basis of Life, Berlin, Germany, July 4-9, 2015
  • Cyclic dipeptides originated from lactic acid bacteria inhibit the growth of multidrug-resistant bacteria, Seoul National University, Republic of Korea, 8th Asian Biophysics Association (ABA) Symposium, Proceedings of ABA Jeju2013 O_12, pp131, Jeju, Republic of Korea, May 26-29, 2013
  • Cyclic dipeptides originated from lactic acid bacteria inhibit the growth of fungi, Seoul National University, Republic of Korea, 8th Asian Biophysics Association (ABA) Symposium, Proceedings of ABA Jeju2013 O_10, pp131, Jeju, Republic of Korea, May 26-29, 2013
  • Putrescine blocks methylglyoxal accumulation, Seoul National University, Republic of Korea, 8th Asian Biophysics Association (ABA) Symposium, Proceedings of ABA Jeju2013 O_9, pp131, Jeju, Republic of Korea, May 26-29, 2013
  • Synergistic effect of cyclic dipeptides originated from lactic acid bacteria, Seoul National University, Republic of Korea, 8th Asian Biophysics Association (ABA) Symposium, Proceedings of ABA Jeju2013 O_8, pp131, Jeju, Republic of Korea, May 26-29, 2013
  • Cyclic dipeptides originated from lactic acid bacteria inhibit the proliferation of influenza A virus, Seoul National University, Republic of Korea, 8th Asian Biophysics Association (ABA) Symposium, Proceedings of ABA Jeju2013 O_1, pp129, Jeju, Republic of Korea, May 26-29, 2013
  • Structural analysis of a cyclic dipeptide as an antifungal substance from lactic acid bacteria, Seoul National University, Republic of Korea, The 24th Synchroton Radiation Users’ Workshop KOSUA Meeting, POSCO International Center, POSTECH, pp168 (PM-16), Republic of Korea, Nov 22, 2012
  • Methylglyoxal Dehydrogenase 1 Regulates Cell Cycle And Apoptosis in Candida albicans, Seoul National University, Republic of Korea, The FEBS JOURNAL 278 (Suppl. 1) 182 (P10.26), The 36th Congress of the Federation of European Biochemical Societies (FEBS Congress), Torino (Turin), Italy, Jun 25-30, 2011
  • Methylglyoxal dehydrogenase 1 regulates cell cycle and apoptosis in Candida albicans, Seoul National University, Republic of Korea, 7th Asian Biophysics Association (ABA) Symposium and Annual Meeting of the Indian Biophysical Society (IBS) by Department of NMR MRI Facility, All India Institute of Medical Sciences, New Delhi-110029, India, pp 123 (P-43), New Delhi, India, Jan 30-Feb 2, 2011
  • NAD -linked methylglyoxal dehydrogenase 2 (alcohol dehydrogenase 1) is involved in normal growth, hyphal formation and virulence in Candida albicans, Seoul National University, Republic of Korea, 2009 International Meeting of the Federation of Korean Microbiological Societies, pp199 (C023), Seoul, Republic of Korea, Oct 22-23, 2009
  • NAD -linked methylglyoxal dehydrogenase 1 regulates cell cycle and apoptosis in Candida albicans, Seoul National University, Republic of Korea, 2009 International Meeting of the Federation of Korean Microbiological Societies, pp199 (C022), Seoul, Republic of Korea, Oct 22-23, 2009
  • Methylglyoxal dehydrogenase 1 regulates cell cycle and apoptosis in Candida albicans, Seoul National University, Republic of Korea, The 16th Annual Meeting of the Korean Biophysical Society, pp90 (P45), Seoul, Republic of Korea, Jun 12, 2009
  • Glutathione reductase is essential for growth and its overexpression leads to defective hyphal growth and attenuated virulence of Candida albicans, Seoul National University, Republic of Korea, The 48th MSK Annual Meeting and 2008 International Symposium on Microbiology, pp210 (E012), Daejeon, Republic of Korea, May 15-16, 2008
  • Purification and characterization of two NAD-Specific methylglyoxal dehydrogenases involved in catalyzing the oxidation of methylglyoxal to pyruvate in Candida albicans, Seoul National University, Republic of Korea, 2007 International Meeting of the Federation of Korean Microbiological Societies, pp199 (C044), Seoul¬¬, Republic of Korea, Oct 11-12, 2007
  • Erythroascorbate peroxidase is involved in cell growth and hyphal formation in Candida albicans, Seoul National University, Republic of Korea, 2006 International Meeting of the Federation of Korean Microbiological Societies, pp184 (D023), Seoul, Republic of Korea, Oct 19-20, 2006
  • Glutathione reductase is essential for growth and its overexpression leads to defective hyphal growth and attenuated virulence of Candida albicans, Seoul National University, Republic of Korea, 2004 International Meeting of the Microbiological Society of Korea, pp216 (F023), Cheonan, Republic of Korea, May 13-14, 2004
  • Glutathione reductase is essential for growth and its overexpression leads to defective hyphal growth and attenuated virulence of Candida albicans, Seoul National University, Republic of Korea, Brain Korea Workshop in Seoul National University, pp1 (I-2), Seoul, Republic of Korea, Jun 24, 2004
  • Physiological roles of erythroascorbate peroxidase in Candida albicans, Seoul National University, Republic of Korea, the 8th Annual Meeting of the Korean Biophysical Society, pp41, Seoul, Republic of Korea, Jun 01, 2001
  • Physiological roles of erythroascorbate peroxidase in Candida albicans, Seoul National University, Republic of Korea, Brain Korea Workshop in Seoul National University, Republic of Korea, pp3 (I-3), Jun 22, 2001
  • Plasma concentrations of amino acids in healthy Korean children by specific area and age groups, Yonsei University, Republic of Korea, 8th Asian Congress of Nutrition, PM01-09, Seoul, Republic of Korea, Aug 29-Sep 2, 1999
  • Age-specific distribution of plasma amino acid concentrations in healthy Korean children, Yonsei University, Republic of Korea, 8th Asian Congress of Nutrition, PM01-12, Seoul, Republic of Korea, Aug 29-Sep 2, 1999

연구실적 (논문: 교신 및 제1저자)

  • Anti-σ factor YlaD regulates transcriptional activity of σ factor YlaC and sporulation via manganese-dependent redox-sensing molecular switch in Bacillus subtilis, Biochemical Journal, 475(13):2127-2151, 2018 (SCI)
  • Antimicrobial activity of cyclic dipeptides produced by Lactobacillus plantarum LBP-K10 against multidrug-resistant bacteria, pathogenic fungi, and influenza A virus, Food Control, 85:223-234, 2018 (SCI)
  • Inducible NAD(H)-linked methylglyoxal oxidoreductase regulates cellular methylglyoxal and pyruvate through enhanced activities of alcohol dehydrogenase and methylglyoxal-oxidizing enzymes in glutathione-depleted Candida albicans, Biochimica et Biophysica Acta (BBA) General Subjects, 1862(1):18-39, 2018 (SCI)
  • Cytochrome c peroxidase regulates intracellular reactive oxygen species and methylglyoxal via enzyme activities of erythroascorbate peroxidase and glutathione-related enzymes in Candida albicans, International Journal of Biochemistry , Cell Biology, 92:183-201, 2017 (SCI)
  • Methylglyoxal synthase regulates cell elongation via alterations of cellular methylglyoxal and spermidine content in Bacillus subtilis, International Journal of Biochemistry , Cell Biology, 91(Pt A):14-28, 2017 (SCI)
  • Methylglyoxal upregulates Dictyostelium discoideum slug migration by triggering glutathione reductase and methylglyoxal reductase activity, International Journal of Biochemistry , Cell Biology, 90:81-92, 2017 (SCI)
  • Proline-Based Cyclic Dipeptides from Korean Fermented Vegetable Kimchi and from Leuconostoc mesenteroides LBP-K06 Have Activities against Multidrug-Resistant Bacteria, Frontiers in Microbiology, 8:761, 2017 (SCIE)
  • Schiff bases of putrescine with methylglyoxal protect from cellular damage caused by accumulation of methylglyoxal and reactive oxygen species in Dictyostelium discoideum, International Journal of Biochemistry , Cell Biology, 86:54-66, 2017 (SCI)
  • Candida albicans glutathione reductase downregulates Efg1-mediated cyclic AMP/protein kinase A pathway and leads to defective hyphal growth and virulence upon decreased cellular methylglyoxal content accompanied by activating alcohol dehydrogenase and glycolytic enzymes, Biochimica et Biophysica Acta (BBA) General Subjects, 1861(4):772-788, 2017 (SCI)
  • Polyamines regulate cell growth and cellular methylglyoxal in high-glucose medium independently of intracellular glutathione, FEBS Letters, 590(6):739–749, 2016 (SCI)
  • Candida albicans erythroascorbate peroxidase regulates intracellular methylglyoxal and reactive oxygen species independently of D-erythroascorbic acid, FEBS Letters, 589(15):1863-1871, http://dx.doi.org/10.1016/j.febslet.2015.04.050, Publisher: Elsevier Science BV Netherlands, ISSN: 0014-5793 (FEBS Lett. 2015 Jul 8;589(15):1863-71, 2015 (SCI)
  • NAD -linked alcohol dehydrogenase 1 regulates methylglyoxal concentration in Candida albicans, FEBS Letters, 588(7):1144-1153, 2014 (SCI)
  • Cyclic dipeptides from lactic acid bacteria inhibit the proliferation of pathogenic fungi, Journal of Microbiology, 52(1):64-70, 2014 (SCIE)
  • Cyclic dipeptides from lactic acid bacteria inhibit proliferation of the influenza A virus, Journal of Microbiology, 51(6):836–843, 2013 (SCIE)

연구실적 (특허)

  • 1) 국제특허등록 (International Patent Registration)
  • - 특허등록, COMPOSITION, CONTAINING CIS-CYCLO(L-LEU-L-PRO) OR CIS-CYCLO(L-PHE-L-PRO), FOR USE AS AN ANTIMICROBIAL AND ANTIVIRAL AGENT, AND PREPARATION METHOD THEREFOR, China Patent Registration No. 201380052609.7, 2018
  • 2) 국내특허등록 (Korea Patent Registration)
  • - 특허등록, 시스-사이클로(L-페닐알라닌-L-프롤린) 를 포함하는 항-인플루엔자 A 바이러스(H3N2) 조성물 및 이의 제조 방법 (Anti-influenza A viral composition comprising cis―cyclo(L―Phe―Pro)and methods of preparation thereof), Republic of Korea Patent No. 10-1782656-0000, 2017
  • - 특허등록, 시스-사이클로(L-페닐알라닌-L-프롤린)의 신규한 용도 (Novel Uses of Cis-Cyclo(L-Phe-L-Pro)), Republic of Korea Patent No. 10-1476054-0000, 2014
  • - 특허등록, 시스-사이클로(L-페닐알라닌-L-프롤린)의 신규한 용도 (Novel Uses of Cis-Cyclo(L-Phe-L-Pro)), Republic of Korea Patent No. 10-1379518-0000, 2014
  • - Seoul National University SNU RDB Foundation (Assignee), IRWEE Co., Ltd. (Patent transfer on Dec 30, 2012) 시스-사이클로(L-루신-L-프롤린) 또는 시스-사이클로(L-페닐알라닌-L-프롤린) 를 포함하는 항균 및 항바이러스제용 조성물 및 이의 제조 방법 (Antibacterial and antiviral composition comprising cis-cyclo(L-Leu-L-Pro) or cis-cyclo(L-Phe-L-Pro) and methods of preparation thereof), Republic of Korea Patent Application No. 10-2012-0111164
  • 4) 국내특허 (Korea patents)
  • 특허출원, 시스-사이클로(L-류신-L-프롤린)를 포함하는 항바이러스제용 조성물 및 이의 제조 방법 (Antiviral composition comprising cis―cyclo(L―Leu―L―Pro)and methods of preparation thereof), Republic of Korea Patent Application No. 10-2017-0016429, 2017
  • 특허출원, 사이클릭 디펩타이드를 합성 효소 (Cyclic dipeptide synthetase), Republic of Korea Patent Application No. 10-2017-0009660, 2017
  • 특허출원, 발효된 유산균이 제거된 배양 배지를 포함하는 유방암 예방 조성물 및 이의 제조방법 (Composition comprising conditioned media being removed Lactobacillus for fermentation amd methods of preparation thereof), Republic of Korea Patent Application No. 10-2017-0009693, 2017
  • 특허출원, 항진균 활성을 가진 시스-사이클로(L-발린-L-프롤린) 및 이의 이용 방법 (cis-cyclo(L-Val-L-Pro) with antifungal activity and methods of using thereof), Republic of Korea Patent Application No. 10-2015-0115675, 2015
  • 특허출원, 사이클릭 디펩타이드 및 DL-3-페닐락틱산을 포함하는 항균, 항진균 및 항바이러스 조성물 (Composition comprising cyclic dipeptides and DL-3-phenyllactic acid for antibacterial, antifungal and antiviral agents), Republic of Korea Patent Application No. 10-2013-0141243, 2013
  • 특허출원, 시스-사이클로(L-페닐알라닌-L-프롤린)의 신규한 용도 (Novel Uses of Cis-Cyclo(L-Phe-L-Pro)), Republic of Korea Patent Application No. 10-2013-0112662, 2013
  • 특허출원, 시스-사이클로(L-발린-L-프롤린)의 신규한 용도 (Novel uses of cis-cyclo(L-Val-L-Pro)), Republic of Korea Patent Application No. 10-2013-0105346, 2013
  • 특허출원, 시스-사이클로(L-루신-L-프롤린) 또는 시스-사이클로(L-페닐알라닌-L-프롤린)를 포함하는 항균 및 항바이러스제용 조성물 및 이의 제조 방법 (Antibacterial and antiviral composition comprising cis-cyclo(L-Leu-L-Pro) or cis-cyclo(L-Phe-L-Pro) and methods of preparation thereof), Republic of Korea Patent Application No. 10-2012-0111164, 2012
  • 특허출원, 시스-사이클로(L-페닐알라닌-L-프롤린)의 신규한 용도 (Novel Uses of Cis-Cyclo(L-Phe-L-Pro)), Republic of Korea Patent Application No. 10-2011-0064091, 2011
  • 5) PCT patents
  • PCT 출원, COMPOSITION, CONTAINING CIS-CYCLO(L-LEU-L-PRO) OR CIS-CYCLO(L-PHE-L-PRO), FOR USE AS AN ANTIMICROBIAL AND ANTIVIRAL AGENT, AND PREPARATION METHOD THEREFOR, PCT Patent Application No. PCT/KR2013/002077, Filed on Mar 15, 2013.
  • PCT 출원, ANTIFUNGAL COMPOSITION COMPRISING CIS-CYCLO(L-PHE-L-PRO) HAVING GENUS GANODERMA FUNGUS-SPECIFIC ANTIFUNGAL ACTIVITY, PCT Patent Application No. PCT/KR2011/004770, Filed on Jun 29, 2011.
  • 6) 국제특허 (International patents)
  • 특허출원, COMPOSITION, CONTAINING CIS-CYCLO(L-LEU-L-PRO) OR CIS-CYCLO(L-PHE-L-PRO), FOR USE AS AN ANTIMICROBIAL AND ANTIVIRAL AGENT, AND PREPARATION METHOD THEREFOR, China Patent Application No. 201380052609.7, Filed on Apr 08, 2015
  • 특허출원 Antifungal composition comprising cis-cyclo (L-Phe-L-Ppro) with antifungal activity against genus Ganoderma, Indonesia Patent Application No. P00 2014 00245, Filed on Jan 16, 2014
  • 특허출원 Antifungal composition comprising cis-cyclo (L-Phe-L-Ppro) with antifungal activity against genus Ganoderma, Malaysia Patent Application No. PI 2013702565, Filed on Dec 26, 2013

수상실적

  • - Worldwide E-book Award, Industrial and Host Associated Stress Responses in Food Microbes. Implications for Food Technology and Food Safety, Frontiers Media SA, Switzerland (ISSN: 288945293X)
  • - Best Conference Presentation Award, 2009 International Meeting of the Federation of Korean Microbiological Societies, Seoul, Republic of Korea
  • - Student Scholarship (B.S.), 1993-1995, Yonsei University
  • - Student Scholarship (M.S.), 1997-1999, Yonsei University
  • - Student Scholarship (Ph.D.), 2001, Seoul National University

연구분야

  • - 대사성질환 및 노화 원인 대사물질의 수용경로와 체내 방어기작
  • - 유용 미생물 유전체 기능 및 저분자 항생 및 항암 물질 탐색
  • - 식품미생물의 고기능성 생리활성 바이오소재 도출 및 개발
리스트